Your Side Effects May IncludePremarin side effects
conjugated estrogens
This side effect is printed on the FDA label for Premarin. It was a question in our daily quiz, where you pick the real side effect from four choices.
A higher risk of dementia in women 65 and older
It comes from the large Women's Health Initiative memory study. It's one of several boxed warnings.
“The WHI Memory Study (WHIMS) estrogen-alone ancillary study of WHI reported an increased risk of probable dementia in postmenopausal women 65 years of age and older”
Use the lowest dose for the shortest time needed. Report unusual vaginal bleeding right away.
133 reports to the FDA's adverse event system mention dementia. A report is not proof the drug caused it. See the query
From quiz No. 18 · October 12, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.