Your Side Effects May Include
Prescription drug · Used for seizures, bipolar disorder and migraine

Depakote side effects

valproate

This side effect is printed on the FDA label for Depakote. It was a question in our daily quiz, where you pick the real side effect from four choices.

An inflamed pancreas that can be fatal

It's a boxed warning. Some cases progressed from first symptoms to death quickly.

From the FDA label
“If pancreatitis is diagnosed, Depakote should ordinarily be discontinued.”
Depakote label, updated Mar 31, 2026 · Read the full label on DailyMed
What to watch for

Get help right away for stomach pain, nausea, vomiting or loss of appetite. It can also cause serious birth defects and liver damage.

630 reports to the FDA's adverse event system mention pancreatitis. A report is not proof the drug caused it. See the query

From quiz No. 18 · October 12, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.