Your Side Effects May IncludeDepo-Provera side effects
medroxyprogesterone
This side effect is printed on the FDA label for Depo-Provera. It was a question in our daily quiz, where you pick the real side effect from four choices.
Thinning bones
It's a boxed warning. The label advises not using it for more than 2 years unless other methods won't work.
“Women who use Depo-Provera Contraceptive Injection (Depo-Provera CI) may lose significant bone mineral density.”
Ask about calcium, vitamin D and how long you should stay on it.
726 reports to the FDA's adverse event system mention bone loss. A report is not proof the drug caused it. See the query
From quiz No. 13 · October 7, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.