Your Side Effects May Include
Prescription drug · Used for depression, often used for sleep

Trazodone (Desyrel) side effects

This side effect is printed on the FDA label for Trazodone. It was a question in our daily quiz, where you pick the real side effect from four choices.

A painful erection that won't go away

Many people take it as a sleep aid. Priapism is rare, but without prompt treatment it can cause permanent damage.

From the FDA label
“Priapism, if not treated promptly, can result in irreversible damage to the erectile tissue.”
Trazodone label, updated Sep 8, 2026 · Read the full label on DailyMed
What to watch for

An erection lasting more than 4 hours is an emergency. Get help right away.

34 reports to the FDA's adverse event system mention priapism. A report is not proof the drug caused it. See the query

From quiz No. 14 · October 8, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.