Your Side Effects May Include
Prescription drug · Used for Parkinson's

Sinemet side effects

carbidopa and levodopa

This side effect is printed on the FDA label for Sinemet. It was a question in our daily quiz, where you pick the real side effect from four choices.

Saliva, sweat or urine that turns dark

Red, brown or even black. The label says it can happen occasionally.

From the FDA label
“Patients should be advised that occasionally, dark color (red, brown, or black) may appear in saliva, urine, or sweat after ingestion of SINEMET.”
Sinemet label, updated Aug 1, 2026 · Read the full label on DailyMed
What to watch for

Tell your doctor about new urges to gamble or spend, or suddenly falling asleep during the day.

125 reports to the FDA's adverse event system mention discolored urine or saliva. A report is not proof the drug caused it. See the query

From quiz No. 14 · October 8, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.