Your Side Effects May IncludeImitrex side effects
sumatriptan
This side effect is printed on the FDA label for Imitrex. It was a question in our daily quiz, where you pick the real side effect from four choices.
Tightness in your chest, throat or jaw
It feels alarming and it's common. The label says it usually isn't the heart, but it can be.
“Sensations of tightness, pain, pressure, and heaviness in the precordium, throat, neck, and jaw commonly occur after treatment with IMITREX tablets and are usually non-cardiac in origin.”
Get help right away for chest pain that is severe or doesn't go away. Don't use it if you have heart disease.
1,135 reports to the FDA's adverse event system mention chest discomfort or throat tightness. A report is not proof the drug caused it. See the query
From quiz No. 9 · October 3, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.