Your Side Effects May Include
Prescription drug · Used for preventing blood clots and stroke

Xarelto side effects

rivaroxaban

This side effect is printed on the FDA label for Xarelto. It was a question in our daily quiz, where you pick the real side effect from four choices.

Bleeding around the spine after an epidural

It's a boxed warning. The bleeding can cause long-term or permanent paralysis.

From the FDA label
“Epidural or spinal hematomas have occurred in patients treated with XARELTO who are receiving neuraxial anesthesia or undergoing spinal puncture.”
Xarelto label, updated Sep 10, 2026 · Read the full label on DailyMed
What to watch for

Tell every doctor you take it before an epidural or spinal tap. Don't stop on your own: stopping early raises stroke risk.

71 reports to the FDA's adverse event system mention spinal or epidural bleeding. A report is not proof the drug caused it. See the query

From quiz No. 13 · October 7, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.