Your Side Effects May IncludeMethotrexate (Trexall) side effects
This side effect is printed on the FDA label for Methotrexate. It was a question in our daily quiz, where you pick the real side effect from four choices.
A deadly overdose from taking it daily instead of weekly
For arthritis it's usually taken once a week. Taking it every day by mistake has killed people.
“Methotrexate tablets when inadvertently administered once daily have resulted in death”
Make sure you know which day of the week to take it, and ask your pharmacist if the label is unclear.
4,942 reports to the FDA's adverse event system mention dosing errors or overdose. A report is not proof the drug caused it. See the query
From quiz No. 11 · October 5, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.