Prescription drug · Used for seizures

Keppra side effects

levetiracetam

This side effect is printed on the FDA label for Keppra. It was a question in our daily quiz, where you pick the real side effect from four choices.

Irritability and aggression

In one study of young children, 12% on Keppra were irritable, compared with none on placebo.

From the FDA label

“Behavioral abnormalities including psychotic symptoms, suicidal ideation, irritability, and aggressive behavior have been observed”

Keppra label, updated Jan 28, 2026 · Read the full label on DailyMed

What to watch for

Tell your doctor about mood or behavior changes, including thoughts of self-harm. Don't stop it suddenly.

3,486 reports to the FDA's adverse event system mention aggression or irritability. A report is not proof the drug caused it. See the query

From quiz No. 11 · October 5, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.