Your Side Effects May IncludeDoxycycline (Vibramycin) side effects
This side effect is printed on the FDA label for Doxycycline. It was a question in our daily quiz, where you pick the real side effect from four choices.
Ulcers in the tube to your stomach
Most people who got them took the pill right before bed.
From the FDA label
“Rare instances of esophagitis and esophageal ulcerations have been reported in patients receiving capsule and tablet forms of the drugs in the tetracycline class.”
Doxycycline label, updated Sep 15, 2026 ·
Read the full label on DailyMed
What to watch for
Take it with a full glass of water and don't lie down right after. It also makes sunburn much more likely.
444 reports to the FDA's adverse event system mention esophagus ulcers or inflammation. A report is not proof the drug caused it. See the query
From quiz No. 10 · October 4, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.