Prescription drug · Used for severe muscle spasticity

Baclofen pump side effects

also sold as Gablofen, Lioresal

This side effect is printed on the FDA label for Baclofen pump. It was a question in our daily quiz, where you pick the real side effect from four choices.

A life-threatening crisis if the pump runs dry

It's a boxed warning. High fever, confusion and rebound stiffness can follow a sudden stop.

From the FDA label

“Abrupt discontinuation of intrathecal baclofen, regardless of the cause, has resulted in sequelae that include high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity”

Baclofen pump label, updated May 7, 2026 · Read the full label on DailyMed

What to watch for

Never miss a refill appointment, and learn your pump's alarm sounds.

1,065 reports to the FDA's adverse event system mention withdrawal. A report is not proof the drug caused it. See the query

From quiz No. 19 · October 13, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.