Your Side Effects May IncludeOtezla side effects
apremilast
This side effect is printed on the FDA label for Otezla. It was a question in our daily quiz, where you pick the real side effect from four choices.
Unexpected weight loss
The label recommends checking weight regularly while taking it.
From the FDA label
“Weight loss may occur in adult or pediatric patients treated with OTEZLA/OTEZLA XR.”
Otezla label, updated Sep 2, 2026 ·
Read the full label on DailyMed
What to watch for
Tell your doctor about unexplained weight loss, or new or worsening depression or thoughts of self-harm.
5,046 reports to the FDA's adverse event system mention weight loss. A report is not proof the drug caused it. See the query
From quiz No. 19 · October 13, 2026 · Play that quiz →
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