Your Side Effects May Include
Prescription drug · Used for an antibiotic for tuberculosis

Rifadin side effects

rifampin

This side effect is printed on the FDA label for Rifadin. It was a question in our daily quiz, where you pick the real side effect from four choices.

Orange tears that can stain contact lenses

Teeth, urine, sweat and tears can all go orange-red. Soft contacts may stay that way.

From the FDA label
“rifampin may produce a discoloration (yellow, orange, red, brown) of the teeth, urine, sweat, sputum, and tears, and the patient should be forewarned of this. Soft contact lenses may be permanently stained.”
Rifadin label, updated Oct 13, 2025 · Read the full label on DailyMed
What to watch for

The color is harmless, but leave soft contacts out. Rifampin can also make birth control pills less effective.

67 reports to the FDA's adverse event system mention discolored urine, tears or teeth, or contact lens trouble. A report is not proof the drug caused it. See the query

From quiz No. 3 · September 27, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.