Your Side Effects May IncludeActos side effects
pioglitazone
This side effect is printed on the FDA label for Actos. It was a question in our daily quiz, where you pick the real side effect from four choices.
A higher risk of bladder cancer
It also carries a boxed warning for heart failure.
From the FDA label
“Bladder cancer: May increase the risk of bladder cancer.”
Actos label, updated Mar 28, 2025 ·
Read the full label on DailyMed
What to watch for
Tell your doctor about blood in your urine or pain when urinating, and about swelling or sudden weight gain.
8,853 reports to the FDA's adverse event system mention bladder cancer. A report is not proof the drug caused it. See the query
From quiz No. 16 · October 10, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.