Your Side Effects May IncludeOmeprazole (Prilosec) side effects
This side effect is printed on the FDA label for Omeprazole. It was a question in our daily quiz, where you pick the real side effect from four choices.
Low magnesium after long-term use
Low magnesium can lead to muscle spasms, an irregular heartbeat and seizures.
“Hypomagnesemia and Mineral Metabolism: Reported rarely with prolonged treatment with PPIs.”
If you've taken it for months, ask whether you still need it. Long-term use is also linked to bone fractures.
2,738 reports to the FDA's adverse event system mention low magnesium. A report is not proof the drug caused it. See the query
From quiz No. 8 · October 2, 2026 · Play that quiz →
More from the drug guide
Drug guide · About · Privacy · Terms · Contact
Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.