Your Side Effects May IncludeLisinopril (Zestril) side effects
also sold as Prinivil
This side effect is printed on the FDA label for Lisinopril. It was a question in our daily quiz, where you pick the real side effect from four choices.
Sudden swelling of the face, lips or tongue
It can happen at any point, even after years on the drug. The same drug is also known for a nagging dry cough.
“Angioedema of the face, extremities, lips, tongue, glottis and/or larynx, including some fatal reactions, have occurred in patients treated with angiotensin converting enzyme inhibitors, including lisinopril, at any time during treatment.”
Swelling of the tongue or throat is an emergency. Call 911 if it affects your breathing.
6,977 reports to the FDA's adverse event system mention angioedema (sudden swelling). A report is not proof the drug caused it. See the query
From quiz No. 5 · September 29, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.