Your Side Effects May Include
Prescription drug · Used for severe long-term pain

Fentanyl patch side effects

also sold as Duragesic

This side effect is printed on the FDA label for Fentanyl patch. It was a question in our daily quiz, where you pick the real side effect from four choices.

A deadly overdose from a hot bath or heating pad

Heat makes the skin absorb more drug from the patch. Saunas, hot tubs and electric blankets are on the list too.

From the FDA label
“Exposure of the fentanyl transdermal system application site and surrounding area to direct external heat sources, such as heating pads or electric blankets, heat or tanning lamps, sunbathing, hot baths, saunas, hot tubs, and heated water beds may increase fentanyl absorption and has resulted in fatal overdose of fentanyl.”
Fentanyl patch label, updated Apr 30, 2026 · Read the full label on DailyMed
What to watch for

Keep heat away from the patch and call your doctor if you get a fever. Keep patches, even used ones, away from children.

1,127 reports to the FDA's adverse event system mention accidental overdose. A report is not proof the drug caused it. See the query

From quiz No. 6 · September 30, 2026 · Play that quiz →

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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.