Your Side Effects May IncludeUloric side effects
febuxostat
This side effect is printed on the FDA label for Uloric. It was a question in our daily quiz, where you pick the real side effect from four choices.
A higher risk of death from heart disease
It's a boxed warning based on a study comparing it with the older gout drug allopurinol.
From the FDA label
“In a cardiovascular (CV) outcome study, gout patients with established CV disease treated with ULORIC had a higher rate of CV death compared to those treated with allopurinol.”
Uloric label, updated Dec 24, 2025 ·
Read the full label on DailyMed
What to watch for
Get help right away for chest pain, shortness of breath or signs of a stroke.
1 reports to the FDA's adverse event system mention a cardiac death. A report is not proof the drug caused it. See the query
From quiz No. 21 · October 15, 2026 · Play that quiz →
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Not medical advice. Don't stop or start a medication because of a quiz. Talk to your doctor or pharmacist. Label text and report counts from openFDA. Not affiliated with any drug maker.